CYC065
Cat. No.：YN290025
CAS No. ：1070790-89-4
规格
价格(RMB)
库存
| 产品名称: | CYC065 |
| CAS No.: | 1070790-89-4 |
| Chemical Name: | (2R,3S)-3-[[6-[[(4,6-dimethyl-3-pyridinyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-2-pentanol |
| Synonyms: | CYC065 |
| 分子量: | 397.52 |
| 分子式: | C₂₁H₃₁N₇O |
| SMILES: | C[C@@H](O)[C@@H](NC1=NC(NCC2=C(C)C=C(C)N=C2)=C3N=CN(C(C)C)C3=N1)CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CYC065 是第二代口服有效的 ATP 竞争性的CDK2/CDK9激酶抑制剂，IC50分别为 5 和 26 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Frame, S., Saladino, C., MacKay, C., et al.Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancerPLoS One15(7),e0234103(2020)
