Ribociclib hydrochloride
Cat. No.：YN290370
CAS No. ：1211443-80-9
规格
价格(RMB)
库存
| 产品名称: | Ribociclib hydrochloride |
| CAS No.: | 1211443-80-9 |
| Chemical Name: | |
| Synonyms: | 瑞博西尼盐酸盐; LEE011 hydrochloride |
| 分子量: | 471.00 |
| 分子式: | C₂₃H₃₁ClN₈O |
| SMILES: | O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ribociclib hydrochloride (LEE011 hydrochloride) 是一种高度特异性的CDK4/6抑制剂，IC50值分别为 10 nM 和 39 nM，对 cyclin B/CDK1 复合体的活性低于其 1000 倍。 |
| IC50和靶点: | [{name:"CDK4:10 nM (IC50)"},{name: "CDK6:39 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
