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GW-1100

Cat. No.:YN321283

  • CAS No. :306974-70-9

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    • 生物活性
    • 参考文献
    • 产品名称: GW-1100
      CAS No.: 306974-70-9
      Chemical Name: 4-[5-[(2-ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]-benzoic acid, ethyl ester
      Synonyms:GW1100;GW1100
      分子量:520.58
      分子式:C₂₇H₂₅FN₄O₄S
      SMILES:O=C1C(CC2=CN=C(N=C2)OCC)=CN(C(SCC3=CC=C(C=C3)F)=N1)C4=CC=C(C(OCC)=O)C=C4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: GW-1100是选择性的GPR40拮抗剂,pIC50为6.9。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Briscoe, C.P., Peat, A.J., McKeown, S.C., et al.Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: Identification of agonist and antagonist small moleculesBr. J. Pharmacol.148(5),619-628(2006)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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