APG-1387
Cat. No.：YN270188
CAS No. ：1570231-89-8
| 产品名称: | APG-1387 |
| CAS No.: | 1570231-89-8 |
| Chemical Name: | |
| Synonyms: | (5S,5'S,8S,8'S,10aR,10a'R)-3,3'-(1,3-phenylenedisulfonyl)bis(N-benzhydryl-5-((S)-2-(methylamino)propanamido)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide);E53VN70K2X;(S,5S,5'S,8S,8'S,10aR,10a'R)-3,3'-(1,3-Phenylenedisulfonyl)bis(N-benzhydryl-5 |
| 分子量: | 1157.40 |
| 分子式: | C₆₀H₇₂N₁₀O₁₀S₂ |
| SMILES: | O=S(C1=CC=CC(S(=O)(N(C[C@@H]2NC([C@@H](NC)C)=O)CC[C@](CC[C@H]3C(NC(C4=CC=CC=C4)C5=CC=CC=C5)=O)([H])N3C2=O)=O)=C1)(N(C[C@@H]6NC([C@@H](NC)C)=O)CC[C@](CC[C@H]7C(NC(C8=CC=CC=C8)C9=CC=CC=C9)=O)([H])N7C6=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | APG-1387 是一种二价 SMAC 模拟物，是IAP拮抗剂，可以诱导 IAP 的蛋白酶体降解。APG-1387 可以增强癌症中免疫介导的细胞凋亡。APG-1387 可用于肝细胞癌，卵巢癌和鼻咽癌的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
