LCL161
Cat. No.：YN270309
CAS No. ：1005342-46-0
规格
价格(RMB)
库存
| 产品名称: | LCL161 |
| CAS No.: | 1005342-46-0 |
| Chemical Name: | N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2S-(methylamino)-propanamide |
| Synonyms: | LCL161;LCL-161;N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N |
| 分子量: | 500.63 |
| 分子式: | C₂₆H₃₃FN₄O₃S |
| SMILES: | C[C@H](NC)C(N[C@@H](C1CCCCC1)C(N2[C@H](C3=NC(C(C4=CC=C(F)C=C4)=O)=CS3)CCC2)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LCL161是IAP的抑制剂，抑制 HEK293 细胞中XIAP和 MDA-MB-231细胞中cIAP1的IC50分别为 35 和 0.4 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Weisberg, E., Ray, A., Barrett, R., et al.Smac mimetics: Implications for enhancement of targeted therapies in leukemiaLeukemia24(12),2100-2109(2010)
