4μ8C
Cat. No.：YN290461
CAS No. ：14003-96-4
| 产品名称: | 4μ8C |
| CAS No.: | 14003-96-4 |
| Chemical Name: | 7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde |
| Synonyms: | IRE1 Inhibitor III |
| 分子量: | 204.18 |
| 分子式: | C₁₁H₈O₄ |
| SMILES: | O=CC1=C(O)C=CC2=C1OC(C=C2C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4μ8C (IRE1 Inhibitor III)是IRE1α的小分子抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
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| Solvent & Solubility: |
Cross, B.C., Bond, P.J., Sadowski, P.G., et al.The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small moleculeProc. Natl. Acad. Sci. USA109(15),E869-878(2012)
Kemp, K.L., Lin, Z., Zhao, F., et al.The serine-threonine kinase inositol-requiring enzyme 1α (IRE1α) promotes IL-4 production in T helper cellsJ. Biol. Chem.288(46),33272-33282(2013)
Lubamba, B.A., Jones, L.C., O'Neal, W.K., et al.X-box-binding protein 1 and innate immune responses of human cystic fibrosis alveolar macrophagesAm. J. Respir. Crit. Care Med.192(12),1449-1461(2015)
