Neostigmine methyl sulfate

Cat. No.：YN380198

CAS No. ：51-60-5

产品名称:	Neostigmine methyl sulfate
CAS No.:	51-60-5
Chemical Name:	3-[[(dimethylamino)carbonyl]oxy]-N,N,N-trimethyl-benzenaminium, methyl sulfate
Synonyms:	甲基硫酸新斯的明
分子量:	334.39
分子式:	C₁₃H₂₂N₂O₆S
SMILES:	C[N+](C)(C)C1=CC=CC(OC(N(C)C)=O)=C1.O=S(OC)([O-])=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 98%

产品描述:	Neostigmine甲基硫酸盐是乙酰胆碱酯酶的可逆抑制剂, 不能穿越血 - 脑屏障。
IC50和靶点:
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In Vivo:
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Milkani, E., Lambert, C.R., and McGimpsey, W.G.Direct detection of acetylcholinesterase inhibitor binding with an enzyme-based surface plasmon resonance sensorAnal. Biochem.408(2),212-219(2011)
Buerkle, H., Boschin, M., Marcus, M.A.E., et al.Central and peripheral analgesia mediated by the acetylcholinesterase-inhibitor neostigmine in the rat inflamed knee joint modelAnesth. Analg.86(5),1027-1032(1998)
Goldstein, G., and Schlesinger, D.H.Thymopoietin and myasthenia gravis: neostigmine-responsive neuromuscular block produced in mice by a synthetic peptide fragment of thymopoietinLancet2(7928),256-259(1975)