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Amiselimod hydrochloride

Cat. No.:YN321087

  • CAS No. :942398-84-7

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    • 产品名称: Amiselimod hydrochloride
      CAS No.: 942398-84-7
      Chemical Name: 2-amino-2-[2-[4-(heptyloxy)-3-(trifluoromethyl)phenyl]ethyl]-1,3-propanediol, monohydrochloride
      Synonyms:MT-1303 hydrochloride
      分子量:413.90
      分子式:C₁₉H₃₁ClF₃NO₃
      SMILES:OCC(CCC1=CC=C(OCCCCCCC)C(C(F)(F)F)=C1)(N)CO.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Amiselimod hydrochloride 是一个新颖的S1P1受体的调节器。
      IC50和靶点:
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      Clinical Trial:
      Solvent & Solubility:
    • Sugahara, K., Maeda, Y., Shimano, K., et al.Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia riskBr. J. Pharmacol.174(1),15-27(2017)

      Shimano, K., Maeda, Y., Kataoka, H., et al.Amiselimod (MT-1303), a novel sphingosine 1-phosphate receptor-1 functional antagonist, inhibits progress of chronic colitis induced by transfer of CD4+CD45RBhigh T cellsPLoS One14(12),e0226154(2019)

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