ML382
Cat. No.：YN480443
CAS No. ：1646499-97-9
规格
价格(RMB)
库存
| 产品名称: | ML382 |
| CAS No.: | 1646499-97-9 |
| Chemical Name: | 2-[(cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)-benzamide |
| Synonyms: | CID71598556;ML 382;ML-382;CID 71598556;CID-71598556 |
| 分子量: | 360.43 |
| 分子式: | C₁₈H₂₀N₂O₄S |
| SMILES: | O=C(NC1=CC=CC=C1OCC)C2=CC=CC=C2NS(=O)(C3CC3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML382 是一种有效选择性的 Mas 相关 G 蛋白偶联受体 X1MRGPRX1 (MrgX1)正向调节剂，EC50为 190 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Wen, W., Wang, Y., Li, Z., et al.Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: A potent and selective positive allosteric modulator of MrgX1ChemMedChem10(1),57-61(2015)
Li, Z., Tseng, P.-Y., Tiwari, V., et al.Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent painProc. Natl. Acad. Sci. USA114(10),E1996-E2005(2017)
