ZL006
Cat. No.:YN360032
CAS No. :1181226-02-7
产品名称: | ZL006 |
CAS No.: | 1181226-02-7 |
Chemical Name: | 4-[[(3,5-dichloro-2-hydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid |
Synonyms: | ZL-006;4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid;ZL006 |
分子量: | 328.15 |
分子式: | C₁₄H₁₁Cl₂NO₄ |
SMILES: | O=C(O)C1=CC=C(NCC2=CC(Cl)=CC(Cl)=C2O)C=C1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ZL006 是 nNOS/PSD-95 相互作用的抑制剂,可抑制nMDA receptor诱导的一氧化氮的合成。 |
IC50和靶点: | |
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Zhou, L., Li, F., Xu, H.-B., et al.Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95Nat. Med.16(12),1439-1443(2010)
Lee, W.-H., Xu, Z., Ashpole, N.M., et al.Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesicsNeuropharmacology97,464-475(2015)