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Transcrocetin

Cat. No.:YN360962

  • CAS No. :27876-94-4

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    • 生物活性
    • 参考文献
    • 产品名称: Transcrocetin
      CAS No.: 27876-94-4
      Chemical Name: 2,6,11,15-tetramethyl-2E,4E,6E,8E,10E,12E,14E-hexadecaheptaenedioic acid
      Synonyms:藏红花酸; trans-Crocetin
      分子量:328.40
      分子式:C₂₀H₂₄O₄
      SMILES:O=C(O)/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Transcrocetin 从藏红花 (Crocus sativus L.) 中提取的,是一种可透过血脑屏障的,高亲和力的NMDA受体拮抗剂。
      IC50和靶点:
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    • Pfister, S.L., Meyer, P., Steck, A., et al.Isolation and structure elucidation of carotenoid−glycosyl esters in gardenia fruits (Gardenia jasminoides Ellis) and saffron (Crocus sativus Linne)J. Agric. Food Chem.44(9),2612-2615(1996)

      Kanakis, C.D., Tarantilis, P.A., Tajmir-Riahi, H.A., et al.Crocetin, dimethylcrocetin, and safranal bind human serum albumin: Stability and antioxidative propertiesJ. Agric. Food Chem.55(3),970-977(2007)

      Oliveira, H., Cai, X., Zhang, Q., et al.Gastrointestinal absorption, antiproliferative and anti-inflammatory effect of the major carotenoids of Gardenia jasminoides Ellis on cancer cellsFood Funct.8(4),1672-1679(2017)

      Nam, K.N., Park, Y.-M., Jung, H.-J., et al.Anti-inflammatory effects of crocin and crocetin in rat brain microglial cellsEur. J. Pharmacol.648(1-3),110-116(2010)

      Zhang, W., Li, Y., and Ge, Z.Cardiaprotective effect of crocetin by attenuating apoptosis in isoproterenol induced myocardial infarction rat modelBiomed. Pharmacother.93,376-382(2017)

      Wang, X., Zhang, G., Qiao, Y., et al.Crocetin attenuates spared nerve injury-induced neuropathic pain in miceJ. Pharmacol. Sci.135(4),141-147(2017)

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