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Linalool

Cat. No.:YN360924

  • CAS No. :78-70-6

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    • 参考文献
    • 产品名称: Linalool
      CAS No.: 78-70-6
      Chemical Name: 3,7-dimethyl-1,6-octadien-3-ol
      Synonyms:Phantol
      分子量:154.25
      分子式:C₁₀H₁₈O
      SMILES:C=CC(O)(C)CC/C=C(C)/C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Linalool 是一种天然单萜类化合物,存在芫荽等植物中,为竞争性的NMDA受体拮抗剂,具有抗肿瘤、抗心脏毒性的作用。Linalool 是一种 PPARα 配体,能降低血浆甲状腺球蛋白 (TG) 水平,改变肝转录组结构和血浆代谢物。
      IC50和靶点:
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    • Hazekamp, A., Tejkalová, K., and Papadimitriou, S.Cannabis: From cultivar to chemovar II—A metabolomics approach to Cannabis classificationCannabis Cannabinoid Res.1(1),202-215(2016)

      Ständer, S., Ständer, H., Seeliger, S., et al.Topical pimecrolimus and tacrolimus transiently induce neuropeptide release and mast cell degranulation in murine skinBr. J. Dermatol.156(5),1020-1026(2007)

      Jun, H.J., Lee, J.H., Kim, J., et al.Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolomeJ. Lipid. Res.55(6),1098-1110(2014)

      Yang, F., Long, E., Wen, J., et al.Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicumParasit. Vectors7,407(2014)

      Jianqun, M., Hai, X., Wu, J., et al.Linalool inhibits cigarette smoke-induced lung inflammation by inhibiting NF-κB activationInt. Immunopharmacol.29(2),708-713(2015)

      Guzmán-Gutiérrez, S.L., Bonilla-Jaime, H., Gómez-Cansino, R., et al.Linalool and β-pinene exert their antidepressant-like activity through the monoaminergic pathwayLife Sci.128,24-29(2015)

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