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(-)-Aspartic acid

Cat. No.:YN360706

  • CAS No. :1783-96-6

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    • 产品名称: (-)-Aspartic acid
      CAS No.: 1783-96-6
      Chemical Name: (-)-Aspartic Acid; (R)-Aspartic Acid; D-(-)-Aspartic Acid; 2-Aminobutanedioic Acid; NSC 97922
      Synonyms:(R)-Aspartic acid; D
      分子量:133.10
      分子式:C₄H₇NO₄
      SMILES:N[C@@H](C(O)=O)CC(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (-)-Aspartic acid 是一种内源性NMDA受体激动剂。
      IC50和靶点:
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    • Zhang, G., and Sun, H.J.Racemization in reverse: Evidence that D-amino acid toxicity on Earth is controlled by bacteria with racemasesPLoS One9(3),e92101(2014)

      D'Aniello, S., Fisher, G.H., Topo, E., et al.N-methyl-D-aspartic acid (NMDA) in the nervous system of the amphioxus Branchiostoma lanceolatumBMC Neurosci.8,109(2007)

      D'Aniello, S., Somorjai, I., Garcia-Fernàndez, J., et al.D-Aspartic acid is a novel endogenous neurotransmitterFASEB J.25(3),1014-1027(2011)

      Usiello, A., Di Fiore, M.M., De Rosa, A., et al.New evidence on the role of D-aspartate metabolism in regulating brain and endocrine system physiology: From preclinical observations to clinical applicationsInt. J. Mol. Sci.21(22),8718(2020)

      Fagg, G.E., and Matus, A.Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densitiesProc. Natl. Acad. Sci. USA81(21),6876-6880(1984)

      Errico, F., Nisticò, R., Palma, G., et al.Increased levels of ᴅ-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibilityMol. Cell Neurosci.37(2),236-246(2008)

      D'Aniello, A., Di Fiore, M.M., Fisher, G.H., et al.Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone releaseFASEB J.14(5),699-714(2000)

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