CCMI
Cat. No.：YN360312
CAS No. ：917837-54-8
| 产品名称: | CCMI |
| CAS No.: | 917837-54-8 |
| Chemical Name: | [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide; XY 4083; AVL 3288 |
| Synonyms: | AVL-3288 |
| 分子量: | 388.25 |
| 分子式: | C₁₉H₁₅Cl₂N₃O₂ |
| SMILES: | O=C(NC1=CC=C(Cl)C=C1)/C(C2=CC(C)=NO2)=C/NC3=CC=C(Cl)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CCMI 是一种有效、选择性的α7 nAChR正向别构调节剂，不是通过正性结合位点与 α7 nAChR 结合并使其激活，能有效正向调节 α7 nAChR 上激动剂诱导的电流。CCMI 在神经系统认知功能紊乱疾病中具有潜在疗效。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ng, H., et al.: Proc. Natl. Acad. Sci. USA., 104, 8059 (2007)
Faghih, R., et al.: J. Med. Chem., 52, 3377 (2009)
