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(+)-Sparteine

Cat. No.:YN361085

  • CAS No. :492-08-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: (+)-Sparteine
      CAS No.: 492-08-0
      Chemical Name: (7R,7aR,14R,14aS)-dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1′,2′-e][1,5]diazocine
      Synonyms:(+)-鹰爪豆碱
      分子量:234.38
      分子式:C₁₅H₂₆N₂
      SMILES:[H][C@]12CCCCN1C[C@H]3C[C@@H]2CN4CCCC[C@@]34[H]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (+)-Sparteine 是一种天然生物碱,作为一种神经节阻滞剂。在神经细胞中,(+)-Sparteine 竞争性地抑制烟碱型乙酰胆碱受体 (nACh receptor) 活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
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      Solvent & Solubility:
    • van Wyk, B.-E., and Verdoorn, G.H.Optical rotation of quinolizidine alkaloids: An important variable in chemosystematic studies of FabaceaePl. Syst. Evol.198(3/4),267-274(1995)

      McSweeney, C.M., Foley, V.M., and McGlacken, G.P.The asymmetric alkylation of dimethylhydrazones; intermolecular chirality transfer using sparteine as chiral ligandChem. Commun. (Camb.)50(94),14817-14819(2014)

      Lin, W., Zhang, K.-F., and Baudoin, O.Regiodivergent enantioselective C-H functionalization of Boc-1,3-oxazinanes and application to the synthesis of β2 and β3-amino acidsNat. Catal.2(10),882-888(2019)

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