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Myosmine

Cat. No.:YN361082

  • CAS No. :532-12-7

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Myosmine
      CAS No.: 532-12-7
      Chemical Name: 3-(3,4-dihydro-2H-pyrrol-5-yl)-pyridine
      Synonyms:麦斯明
      分子量:146.19
      分子式:C₉H₁₀N₂
      SMILES:C1(C2=NCCC2)=CN=CC=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Myosmine 是存在于坚果和坚果制品中的特定烟草生物碱,对 a4b2 烟碱乙酰胆碱受体 (nAChR) 具有低亲和力,Ki值为 3300 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Zaveri, N., Jiang, F., Olsen, C., et al.Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluationJ. Med. Chem.53(22),8187-8191(2010)

      Tyroller, S., Zwickenpflung, W., and Richter, E.New sources of dietary myosmine uptake from cereals, fruits, vegetables, and milkJ. Agric. Food Chem.50(17),4909-4915(2002)

      Ferretti, G., Dukat, M., Giannella, M., et al.Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptorsBioorg. Med. Chem. Lett.13(4),733-735(2003)

      Zwickenpflung, W., Tyroller, S., and Richter, E.Metabolism of myosmine in wistar ratsDrug Metab. Dispos.33(11),1648-1656(2005)

      Hecht, S.S., Han, S., Kenney, P.M.J., et al.Investigation of the reaction of myosmine with sodium nitrite in vitro and in ratsChem. Res. Toxicol.20(3),543-549(2007)

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