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Mivacurium dichloride

Cat. No.:YN360883

  • CAS No. :106861-44-3

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Mivacurium dichloride
      CAS No.: 106861-44-3
      Chemical Name: (1R,1’R)-2,2’-[[(4E)-1,8-dioxo-4-octene-1,8-diyl]bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl] isoquinolinium, dichloride
      Synonyms:米库氯铵,Mivacurium chloride,二氯美维库铵
      分子量:1100.17
      分子式:C₅₈H₈₀Cl₂N₂O₁₄
      SMILES:O=C(OCCC[N+]1(C)[C@H](CC2=CC(OC)=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)CC/C=C/CCC(OCCC[N+]4(C)[C@H](CC5=CC(OC)=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4)=O.[Cl-].[Cl-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Mivacurium dichloride 是一种苄基异喹啉衍生物,也是一种短效非去极化神经肌肉阻滞剂和骨骼肌松弛剂。Mivacurium dichloride 可与nAChR偶联,以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Okanlami, O.A., Fryer, A.D., and Hirshman, C.Interaction of nondepolarizing muscle relaxants with M2 and M3 muscarinic receptors in guinea pig lung and heartAnesthesiology84(1),155-161(1996)

      Johnsson, M., Gurley, D., Dabrowski, M., et al.Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: A possible explanation for the train-of-four fadeAnesthesiology105(3),521-533(2006)

      Clutton, R.E., and Glasby, M.A.A comparison of the neuromuscular and cardiovascular effects of vecuronium, atracurium and mivacurium in sheepRes. Vet. Sci.64(3),233-237(1998)

      Zeng, R., Liu, X., Zhang, J., et al.The efficacy and safety of mivacurium in pediatric patientsBMC Anesthesiol.17(1),58(2017)

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