SB 202190
Cat. No.：YN350025
CAS No. ：152121-30-7
| 产品名称: | SB 202190 |
| CAS No.: | 152121-30-7 |
| Chemical Name: | 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol |
| Synonyms: | FHPI,SB202190 |
| 分子量: | 331.34 |
| 分子式: | C₂₀H₁₄FN₃O |
| SMILES: | FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB 202190 是选择性的p38 MAPK抑制剂，抑制 p38α 和 p38β2 的IC50分别为 50 nM 和 100 nM。SB 202190 与重组人活性 p38 激酶的 ATP 袋结合，Kd值为 38 nM。SB 202190 具有抗癌活性并可以挽救记忆障碍。 |
| IC50和靶点: | [{name:"p38α:50 nM (IC50)"},{name: "p38β2:100 nM (IC50)"}] |
| In Vitro: | |
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| Solvent & Solubility: |
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