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Skepinone-L

Cat. No.:YN350158

  • CAS No. :1221485-83-1

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    • 参考文献
    • 产品名称: Skepinone-L
      CAS No.: 1221485-83-1
      Chemical Name: 2-[(2,4-difluorophenyl)amino]-7-[(2R)-2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one
      Synonyms:CBS3830
      分子量:425.42
      分子式:C₂₄H₂₁F₂NO₄
      SMILES:O=C1C2=CC(OC[C@@H](CO)O)=CC=C2CCC3=C1C=CC(NC4=CC=C(C=C4F)F)=C3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Skepinone-L (CBS3830) 是选择性p38 MAPK抑制剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Suzuki, O., Katsumata, Y., and Oya, M.Oxidation of β-phenylethylamine by both types of monoamine oxidase: Examination of enzymes in brain and liver mitochondria of eight speciesJ. Neurochem.36(3),1298-1301(1981)

      Yang, H.Y., and Neff, N.H.β-Phenylethylamine: A specific substrate for type B monoamine oxidase of brainJ. Pharmacol. Exp. Ther.187(2),365-371(1973)

      Kim, D., Kowalchick, J.E., Edmondson, S.D., et al.Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIAT (sitagliptin phosphate)Bioorg. Med. Chem. Lett.17(12),3373-3377(2007)

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