AL 8697
Cat. No.：YN350059
| 产品名称: | AL 8697 |
| CAS No.: | 1057394-06-5 |
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| 分子量: | 402.41 |
| 分子式: | C₂₁H₂₁F₃N₄O |
| SMILES: | O=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AL 8697 是一种特异性的，具有口服活性的p38α MAPK抑制剂，IC50为 6 nM。与 p38β (IC50=82 nM) 相比，AL 8697 对 p38α 的抑制作用强 14 倍，对 p38α 的选择性比其他 91 种激酶高 300 倍。具有抗炎活性。 |
| IC50和靶点: | [{name:"p38α:6 nM (IC50)"},{name: "p38β:82 nM (IC50)"}] |
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