URB-597
Cat. No.：YN370427
CAS No. ：546141-08-6
| 产品名称: | URB-597 |
| CAS No.: | 546141-08-6 |
| Chemical Name: | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate |
| Synonyms: | KDS-4103 |
| 分子量: | 338.40 |
| 分子式: | C₂₀H₂₂N₂O₃ |
| SMILES: | O=C(OC1=CC(C2=CC=CC(C(N)=O)=C2)=CC=C1)NC3CCCCC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | URB597是口服生物相容性的FAAH抑制剂，IC50为4.6 nM，对其它的cannabinoid-相关靶点无活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kathuria, S., Gaetani, S., Fegley, D., et al.Modulation of anxiety through blockade of anandamide hydrolysisNat. Med.1(9),76-81(2003)
Cravatt, B.F., Giang, D.K., Mayfield, S.P., et al.Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amidesNature384,83-87(1996)
Cravatt, B.F., Demarest, K., Patricelli, M.P., et al.Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolaseProc. Natl. Acad. Sci. USA98(16),9371-9376(2001)
