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Biochanin A

Cat. No.:YN372213

  • CAS No. :491-80-5

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    • 生物活性
    • 参考文献
    • 产品名称: Biochanin A
      CAS No.: 491-80-5
      Chemical Name: 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:4-Methylgenistein; Olmelin
      分子量:284.26
      分子式:C₁₆H₁₂O₅
      SMILES:OC1=C2C(OC=C(C3=CC=C(OC)C=C3)C2=O)=CC(O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Biochanin A 是一种天然存在的脂肪酸酰胺水解酶 (FAAH) 抑制剂,抑制FAAH,作用于小鼠,大鼠,人 FAAH,IC50分别为 1.8,1.4 和 2.4 μM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Evans, B.A., Griffiths, K., and Morton, M.S.Inhibition of 5α-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoidsJ. Endocrinol.147(2),295-302(1995)

      Khan, S.I., Zhao, J., Khan, I.A., et al.Potential utility of natural products as regulators of breast cancer-associated aromatase promotersReprod. Biol. Endocrinol.9:91,(2011)

      Patisaul, H.B., and Jefferson, W.The pros and cons of phytoestrogensFront. Neuroendocrinol.31(4),400-419(2010)

      Wang, L., Waltenberger, B., Pferschy-Wenzig, E.M., et al.Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): A reviewBiochem. Pharmacol.92(1),73-89(2014)

      Rasbach, K.A., and Schnellmann, R.G.Isoflavones promote mitochondrial biogenesisJ. Pharmacol. Exp. Ther.325(2),536-543(2008)

      Thors, L., Burston, J.J., Alter, B.J., et al.Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolaseBr. J. Pharmacol.160(3),549-560(2010)

      Medjakovic, S., and Jungbauer, A.Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptorJ. Steroid Biochem. Mol. Biol.108(1-2),171-177(2008)

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