PF-04457845
Cat. No.：YN372200
CAS No. ：1020315-31-4
| 产品名称: | PF-04457845 |
| CAS No.: | 1020315-31-4 |
| Chemical Name: | N-3-pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide |
| Synonyms: | PF-4457845 |
| 分子量: | 455.43 |
| 分子式: | C₂₃H₂₀F₃N₅O₂ |
| SMILES: | O=C(NC1=NN=CC=C1)N(CC/2)CCC2=C\C3=CC=CC(OC4=NC=C(C(F)(F)F)C=C4)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-04457845 是一种高效选择性的FAAH抑制剂，作用于hFAAH和rFAAH，IC50分别为 7.2±0.63 nM 和 7.4±0.62 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Johnson, D.S., Stiff, C., Lazerwith, S.E., et al.Discovery of PF-04457845: A highly potent, orally bioavailable, and selective urea FAAH inhibitorACS Med. Chem. Lett.2(2),91-96(2011)
