PF 750
Cat. No.:YN372470
CAS No. :959151-50-9
产品名称: | PF 750 |
CAS No.: | 959151-50-9 |
Chemical Name: | N-phenyl-4-(quinolin-2-ylmethyl)piperidine-1-carboxamide |
Synonyms: | ZINC27647189,UNII-7756CPP14K,PF-750 |
分子量: | 345.44 |
分子式: | C₂₂H₂₃N₃O |
SMILES: | O=C(NC1=CC=CC=C1)N(CC2)CCC2CC3=CN=C4C(C=CC=C4)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PF 750 是一种选择性的、共价的脂肪酸酰胺水解酶(FAAH)的抑制剂,不同预孵育时间下的IC50值为 16.2-595 nM。共价修饰酶活性位点的丝氨酸亲核体。 |
IC50和靶点: | |
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Ahn, K., Johnson, D.S., Fitzgerald, L.R., et al.Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivityBiochemistry46,13019-13030(2007)