BRD0705
Cat. No.：YN420097
CAS No. ：2056261-41-5
规格
价格(RMB)
库存
| 产品名称: | BRD0705 |
| CAS No.: | 2056261-41-5 |
| Chemical Name: | |
| Synonyms: | BRD-0705;BRD 0705 |
| 分子量: | 321.42 |
| 分子式: | C₂₀H₂₃N₃O |
| SMILES: | O=C1C2=C(N=C3C([C@]2(CC)C4=CC=CC=C4)=CNN3)CC(C)(C)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BRD0705 是一种有效的，具有旁系选择性和口服活性的GSK3α抑制剂，IC50为 66 nM，Kd为 4.8 μM。 BRD0705 与 GSK3β (IC50为 515 nM) 相比，对GSK3α的选择性更高 (8 倍)。BRD0705 可用于急性髓细胞性白血病的研究。 |
| IC50和靶点: | [{name:"GSK3α:66 nM (IC50)"},{name: "GSK3α:4.8 μM (Kd)"},{name: "GSK-3β(WT):515 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
