GSK467
Cat. No.：YN310143
CAS No. ：1628332-52-4
| 产品名称: | GSK467 |
| CAS No.: | 1628332-52-4 |
| Chemical Name: | |
| Synonyms: | GSK467;GSK 467;2-[(1-Benzyl-1h-Pyrazol-4-Yl)oxy]pyrido[3,4-D]pyrimidin-4(3h)-One;2-[(1-Benzyl-1H-pyrazol-4-yl)oxy]-pyrido-[3,4-d]pyrimidin-4(3H)-one;ZTYRLXUTLYBVHH-UHFFFAOYSA-N;GSK467; GSK 467;BCP30840;J3.601.422I;Q27460958;2-[(1-benzyl-1H-pyrazol-4-yl)ox |
| 分子量: | 319.32 |
| 分子式: | C₁₇H₁₃N₅O₂ |
| SMILES: | O=C1C2=C(NC(OC3=CN(N=C3)CC4=CC=CC=C4)=N1)C=NC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK467 是一种细胞渗透性的，有效选择性的KDM5B (JARID1B or PLU1)抑制剂，Ki值为 10 nM，是 KDM4C 选择性的 180 倍，而对 KDM6 或其他 Jumonji 家族成员没有明显的抑制作用。 |
| IC50和靶点: | [{name:"KDM5:10 nM (Ki)"},{name: "KDM5:26 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
