IPA-3
Cat. No.：YN290361
CAS No. ：42521-82-4
规格
价格(RMB)
库存
| 产品名称: | IPA-3 |
| CAS No.: | 42521-82-4 |
| Chemical Name: | 1,1'-dithiobis-2-naphthalenol |
| Synonyms: | IPA 3,IPA3 |
| 分子量: | 350.45 |
| 分子式: | C₂₀H₁₄O₂S₂ |
| SMILES: | OC1=CC=C2C=CC=CC2=C1SSC3=C4C=CC=CC4=CC=C3O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | IPA-3 是一种选择性的，ATP 非竞争的PAK1抑制剂，IC50值为 2.5 μM，对 PAKs 4-6 没有抑制作用。 |
| IC50和靶点: | [{name:"PAK1:2.5 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kumar, R., Gururaj, A.E., and Barnes, C.J.p21-activated kinases in cancerNat. Rev. Cancer6(6),459-471(2006)
Deacon, S.W., Beeser, A., Fukui, J.A., et al.An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinaseChem. Biol.15(4),322-331(2008)
Viaud, J., and Peterson, J.R.An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalentlyMol. Cancer Ther.8(9),2559-2565(2009)
