Purmorphamine
Cat. No.：YN450093
CAS No. ：483367-10-8
规格
价格(RMB)
库存
| 产品名称: | Purmorphamine |
| CAS No.: | 483367-10-8 |
| Chemical Name: | 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine |
| Synonyms: | Shh Signaling Antagonist VI |
| 分子量: | 520.62 |
| 分子式: | C₃₁H₃₂N₆O₂ |
| SMILES: | N1(C2=CC=C(NC3=NC(OC4=CC=CC5=C4C=CC=C5)=NC6=C3N=CN6C7CCCCC7)C=C2)CCOCC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Purmorphamine (Shh Signaling Antagonist VI) 是一种平滑受体激动剂，EC50为 1 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Wu, X., Ding, Q., Gray, N.S., et al.A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cellsJ. Am. Chem. Soc.124(49),14520-14521(2002)
Beloti, M.M., Bellesini, L.S., and Rosa, A.L.Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cellsCell Biol. Int.29(7),537-541(2005)
Wu, X., Walker, J., Zhang, J., et al.Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathwayChem. Biol.11(9),1229-1238(2004)
Sinha, S., and Chen, J.K.Purmorphamine activates the hedgehog pathway by targeting smoothenedNat. Chem. Biol.2(1),29-30(2006)
