Sonidegib diphosphate
Cat. No.：YN450117
CAS No. ：1218778-77-8
规格
价格(RMB)
库存
| 产品名称: | Sonidegib diphosphate |
| CAS No.: | 1218778-77-8 |
| Chemical Name: | rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide, diphosphate |
| Synonyms: | Erismodegib diphosphate; LDE225 diphosphate; NVP-LDE225 diphosphate |
| 分子量: | 681.49 |
| 分子式: | C₂₆H₃₂F₃N₃O₁₁P₂ |
| SMILES: | O=C(C1=C(C)C(C(C=C2)=CC=C2OC(F)(F)F)=CC=C1)NC3=CC=C(N=C3)N4C[C@@H](C)O[C@@H](C)C4.O=P(O)(O)O.O=P(O)(O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sonidegib diphosphate (Erismodegib diphosphate) 是一种有效，选择性的Smo拮抗剂，抑制鼠和人Smo的IC50分别为 1.3 nM 和 2.5 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Pan, S., Wu, X., Jiang, J., et al.Discovery of NVP-LDE225, a potent and selective smoothened antagonistACS Med. Chem. Lett.1(3),130-134(2010)
