Sonidegib
Cat. No.：YN450118
CAS No. ：956697-53-3
规格
价格(RMB)
库存
| 产品名称: | Sonidegib |
| CAS No.: | 956697-53-3 |
| Chemical Name: | rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225; Odomzo; |
| Synonyms: | Erismodegib; LDE225; NVP-LDE225 |
| 分子量: | 485.50 |
| 分子式: | C₂₆H₂₆F₃N₃O₃ |
| SMILES: | O=C(C1=C(C)C(C(C=C2)=CC=C2OC(F)(F)F)=CC=C1)NC3=CC=C(N=C3)N4C[C@@H](C)O[C@@H](C)C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sonidegib (Erismodegib) 是一种有效，选择性的Smo拮抗剂，抑制鼠和人Smo的IC50分别为 1.3 nM 和 2.5 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Berman, D., et al.: Science, 297, 1559 (2002), Varjosalo, M., et al.: Cell, 133, 537 (2008), Theunissen, J., et al.: Cancer Res., 69, 6007 (2009),
