AEE788
Cat. No.：YN340004
CAS No. ：497839-62-0
规格
价格(RMB)
库存
| 产品名称: | AEE788 |
| CAS No.: | 497839-62-0 |
| Chemical Name: | 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Synonyms: | NVP-AEE 788 |
| 分子量: | 440.58 |
| 分子式: | C₂₇H₃₂N₆ |
| SMILES: | C[C@H](C1=CC=CC=C1)NC2=C(C=C3C(C=C4)=CC=C4CN5CCN(CC)CC5)C(N3)=NC=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AEE788是EGFR和ErbB2的抑制剂，IC50值分别为2和6 nM。 |
| IC50和靶点: | [{name:"EGFR:2 nM (IC50)"},{name: "ErbB2:6 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Traxler, P., Allegrini, P.R., Brandt, R., et al.AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activityCancer Res.64(14),4931-4941(2004)
