Almonertinib mesylate
Cat. No.：YN340346
CAS No. ：2134096-06-1
规格
价格(RMB)
库存
| 产品名称: | Almonertinib mesylate |
| CAS No.: | 2134096-06-1 |
| Chemical Name: | |
| Synonyms: | HS-10296 mesylate |
| 分子量: | 621.76 |
| 分子式: | C31H39N7O5S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Almonertinib (HS-10296) mesylate 是一种口服、不可逆的第三代EGFR酪氨酸激酶抑制剂，对EGFR致敏和 T790M 耐药突变具有高选择性。Almonertinib mesylate 对 T790M、T790M/L858R 和 T790M/Del19 表现出较强的抑制活性 (IC50分别为 0.37、0.29 和 0.21 nM)，对野生型的抑制作用较弱 (3.39 nM)。Almonertinib mesylate 用于非小细胞肺癌的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
