AV-412 free base
Cat. No.：YN340046
CAS No. ：451492-95-8
规格
价格(RMB)
库存
| 产品名称: | AV-412 free base |
| CAS No.: | 451492-95-8 |
| Chemical Name: | |
| Synonyms: | MP-412 free base |
| 分子量: | 507.00 |
| 分子式: | C₂₇H₂₈ClFN₆O |
| SMILES: | O=C(C=C)NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1C#CC(C)(C)N(CC4)CCN4C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AV-412 free base (MP-412 free base) 是EGFR抑制剂，抑制EGFR，EGFRL858R，EGFRT790M，EGFRL858R/T790M和 ErbB2的IC50值分别为0.75，0.5，0.79，2.3，19 nM。 |
| IC50和靶点: | [{name:"EGFR:0.75 nM (IC50)"},{name: "ErbB2:19 nM (IC50)"},{name: "EGFRL858R:0.51 nM (IC50)"},{name: "EGFRL858R/T790M:2.3 nM (IC50)"},{name: "EGFRT790M:0.79 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
