PKI-166
Cat. No.：YN340086
CAS No. ：187724-61-4
| 产品名称: | PKI-166 |
| CAS No.: | 187724-61-4 |
| Chemical Name: | 4-[4-[[(1R)-1-phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-phenol |
| Synonyms: | |
| 分子量: | 330.38 |
| 分子式: | C₂₀H₁₈N₄O |
| SMILES: | OC1=CC=C(C2=CC3=C(N=CN=C3N2)N[C@@H](C4=CC=CC=C4)C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PKI-166 是一种高效、选择性的，有口服生物活性的EGFR 酪氨酸激酶抑制剂，IC50值为 0.7 nM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bruns, C.J., Solorzano, C.C., Harbison, M.T., et al.Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinomaCancer Res.60(11),2926-2935(2000)
