AG 555
Cat. No.：YN340172
CAS No. ：133550-34-2
| 产品名称: | AG 555 |
| CAS No.: | 133550-34-2 |
| Chemical Name: | (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide |
| Synonyms: | Tyrphostin B46 |
| 分子量: | 322.36 |
| 分子式: | C₁₉H₁₈N₂O₃ |
| SMILES: | O=C(NCCCC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AG 555 (Tyrphostin AG 555) 是一种有效的抗逆转录病毒药物，是一种有效的选择性EGFR抑制剂，可阻断Cdk2活化。 |
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Gazit, A., Osherov, N., Posner, I., et al.Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinasesJ. Med. Chem.34(6),1896-1907(1991)
Ben-Bassat, H., Vardi, D.V., Gazit, A., et al.Tyrphostins suppress the growth of psoriatic keratinocytesExp. Dermatol.4(2),82-88(1995)
Esther, A., Iftach, S., and Esther, P.Inhibition of Moloney murine leukemia virus replication by tyrphostins, tyrosine kinase inhibitorsFEBS Lett.341(1),99-103(1994)
