Tephrosin
Cat. No.：YN340268
| 产品名称: | Tephrosin |
| CAS No.: | 76-80-2 |
| Chemical Name: | (7aR,13aR)-13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one |
| Synonyms: | 灰叶草素; Deguelinol I; Hydroxydeguelin |
| 分子量: | 410.42 |
| 分子式: | C₂₃H₂₂O₇ |
| SMILES: | O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tephrosin 是一种天然类胡萝卜素，具有较强的抗肿瘤活性。Tephrosin 通过诱导受体内化来诱导EGFR和ErbB2的降解。 |
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Fang, N., and Casida, J.E.Anticancer action of cubé insecticide: Correlation for rotenoid constituents between inhibition of NADH: Ubiquinone oxidoreductase and induced ornithine decarboxylase activitiesProc. Natl. Acad. Sci. USA95,3380-3384(1998)
Choi, Y., and Lee, J.H.The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cellsCancer Biol.Ther.12(11),989-996(2011)
