Toceranib phosphate
Cat. No.：YN440078
CAS No. ：874819-74-6
规格
价格(RMB)
库存
| 产品名称: | Toceranib phosphate |
| CAS No.: | 874819-74-6 |
| Chemical Name: | |
| Synonyms: | SU11654 phosphate; PHA 291639E phosphate |
| 分子量: | 494.45 |
| 分子式: | C₂₂H₂₈FN₄O₆P |
| SMILES: | O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C.O=P(O)(O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Toceranib phosphate (SU11654 phosphate) 是一种具有口服活性的酪氨酸激酶 (RTK) 受体抑制剂，能有效抑制PDGFR，VEGFR，Kit，抑制 PDGFRβ 和 Flk-1/KDR 的Ki值分别为 5 nM 和 6 nM。Toceranib phosphate 具有抗肿瘤和抗血管生成活性，可用于犬肥大细胞肿瘤的研究。 |
| IC50和靶点: | [{name:"PDGFRβ:5 nM (Ki)"},{name: "Flk-1:6 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
