Sulfatinib
Cat. No.:YN440202
| 产品名称: | Sulfatinib |
| CAS No.: | 1308672-74-3 |
| Chemical Name: | N-[2-(dimethylamino)ethyl]-3-[[4-[(2-methyl-1H-indol-5-yl)oxy]-2-pyrimidinyl]amino]-benzenemethanesulfonamide |
| Synonyms: | HMPL-012 |
| 分子量: | 480.58 |
| 分子式: | C₂₄H₂₈N₆O₃S |
| SMILES: | O=S(CC1=CC=CC(NC2=NC=CC(OC3=CC4=C(NC(C)=C4)C=C3)=N2)=C1)(NCCN(C)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sulfatinib (HMPL-012) 是一种有效且高度选择性的针对VEGFR1/2/3,FGFR1和CSF1R的酪氨酸激酶抑制剂,IC50值在1 到 24 nM之间。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Qi, C., and Xu, J.Method of treating solid tumorsWO2018090324A1,(2018)