Alofanib
Cat. No.：YN440369
CAS No. ：1612888-66-0
规格
价格(RMB)
库存
| 产品名称: | Alofanib |
| CAS No.: | 1612888-66-0 |
| Chemical Name: | 3-[[[4-methyl-2-nitro-5-(3-pyridinyl)phenyl]amino]sulfonyl]-benzoic acid |
| Synonyms: | RPT835 |
| 分子量: | 413.40 |
| 分子式: | C₁₉H₁₅N₃O₆S |
| SMILES: | O=C(O)C1=CC=CC(S(=O)(NC2=CC(C3=CC=CN=C3)=C(C)C=C2[N+]([O-])=O)=O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Alofanib (RPT835)是高效和选择性的成纤维细胞生长因子受体2 (FGFR2) 的变构抑制剂。抗癌活性。抗血管生成活性。 |
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Khochenkov, D.A., Solomko, E.S., Peretolchina, N.M., et al.Antiangiogenic activity of alofanib, an allosteric inhibitor of fibroblast growth factor receptor 2Bull. Exp. Biol. Med.160(1),84-87(2015)
Tsimafeyeu, I., Ludes-Meyers, J., Stepanova, E., et al.Targeting FGFR2 with alofanib (RPT835) shows potent activity in tumour modelsEur. J. Cancer61,20-28(2016)
