UNC0379
Cat. No.：YN310164
CAS No. ：1620401-82-2
规格
价格(RMB)
库存
| 产品名称: | UNC0379 |
| CAS No.: | 1620401-82-2 |
| Chemical Name: | 6,7-dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]-4-quinazolinamine |
| Synonyms: | UNC 0379; UNC-0379 |
| 分子量: | 413.56 |
| 分子式: | C₂₃H₃₅N₅O₂ |
| SMILES: | COC1=C(OC)C=C2C(N=C(N3CCCC3)N=C2NCCCCCN4CCCC4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | UNC0379 是一个选择性的底物竞争性的赖氨酸甲基转移酶SETD8(KMT5A) 抑制剂，IC50值为 7.3 μM，对其他 15 种甲基转移酶有很好的选择性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ma, A., Yu, W., Li, F., et al.Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8J. Med. Chem.,(2014)
