SGC707
Cat. No.：YN310328
CAS No. ：1687736-54-4
| 产品名称: | SGC707 |
| CAS No.: | 1687736-54-4 |
| Chemical Name: | N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea |
| Synonyms: | SGC 707,SGC707 |
| 分子量: | 298.34 |
| 分子式: | C₁₆H₁₈N₄O₂ |
| SMILES: | O=C(NCC(N1CCCC1)=O)NC2=CC=C3C=NC=CC3=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SGC707是一种PRMT3化学探针, 是强效的选择性和具有细胞活性的PRMT3变构抑制剂, IC50值为31 nM。 |
| IC50和靶点: | [{name:"PRMT3:31 nM (IC50)"}] |
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| Solvent & Solubility: |
Tang, J., Gary, J.D., Clarke, S., et al.PRMT3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulationJ. Biol. Chem.273(27),16935-16945(1998)
Wolf, S.S.The protein arginine methyltransferase family: An update about function, new perspectives and the physiological role in humansCell. Mol. Life Sci.66(13),2109-2121(2009)
