CARM1-IN-1
Cat. No.:YN310186
CAS No. :1020399-49-8
产品名称: | CARM1-IN-1 |
CAS No.: | 1020399-49-8 |
Chemical Name: | 3,5-bis[(3-bromo-4-hydroxyphenyl)methylene]-1-(phenylmethyl)-4-piperidinone |
Synonyms: | CARM1-IN-7G |
分子量: | 555.26 |
分子式: | C₂₆H₂₁Br₂NO₃ |
SMILES: | O=C1/C(CN(CC2=CC=CC=C2)C/C1=C\C3=CC=C(O)C(Br)=C3)=C/C4=CC=C(O)C(Br)=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CARM1-IN-1是CARM1高效选择性抑制剂,IC50值为8.6uM,对PRMT1和SET7抑制活性很抵。 |
IC50和靶点: | |
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Cheng, D., Valente, S., Castellano, S., et al.Novel 3,5-Bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: Enzyme selectivity and cellular activityJ. Med. Chem.54(13),4982-4932(2011)