Ningetinib
Cat. No.：YN440109
CAS No. ：1394820-69-9
规格
价格(RMB)
库存
| 产品名称: | Ningetinib |
| CAS No.: | 1394820-69-9 |
| Chemical Name: | N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide |
| Synonyms: | 宁格替尼 |
| 分子量: | 556.58 |
| 分子式: | C₃₁H₂₉FN₄O₅ |
| SMILES: | CC1=C(C(NC2=CC(F)=C(OC3=CC=NC4=C3C=CC(OCC(C)(O)C)=C4)C=C2)=O)C(N(C5=CC=CC=C5)N1C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ningetinib 是一种有效的口服生物可用的小分子酪氨酸激酶抑制剂 (TKI)，对c-Met，VEGFR2和Axl的IC50值分别为 6.7, 1.9 和 <1.0 nM。 |
| IC50和靶点: | [{name:"VEGFR2:1.9 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Xi, N.Substituted quinoline compounds and methods of useUS20120219522A1,(2012)
