NVP-BVU972
Cat. No.：YN440319
CAS No. ：1185763-69-2
规格
价格(RMB)
库存
| 产品名称: | NVP-BVU972 |
| CAS No.: | 1185763-69-2 |
| Chemical Name: | 6-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]-quinoline |
| Synonyms: | NVP-BVU 972 |
| 分子量: | 340.38 |
| 分子式: | C₂₀H₁₆N₆ |
| SMILES: | CN1N=CC(C2=NN3C(C=C2)=NC=C3CC4=CC=C(N=CC=C5)C5=C4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NVP-BVU972是高活性Met抑制剂，IC50为14 nM，对其它的激酶抑制性较低。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tiedt, R., Degenkolbe, E., Furet, P., et al.A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patientsCancer Res.71(15),5255-5264(2011)
