PF-04217903
Cat. No.：YN440180
CAS No. ：956905-27-4
规格
价格(RMB)
库存
| 产品名称: | PF-04217903 |
| CAS No.: | 956905-27-4 |
| Chemical Name: | 4-[1-(6-quinolinylmethyl)-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanol |
| Synonyms: | PF04217903; PF 04217903 |
| 分子量: | 372.38 |
| 分子式: | C₁₉H₁₆N₈O |
| SMILES: | OCCN1N=CC(C2=NC3=C(N=C2)N=NN3CC4=CC5=CC=CN=C5C=C4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-04217903 是一种高效的 ATP 竞争性c-Met激酶抑制剂，Ki为 4.8 nM。PF-04217903 相对于 208 个激酶显示出 1000 倍以上的选择性。具有抗血管生成特性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Zou, H.Y., Li, Q., Lee, J.H., et al.Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitorMol. Cancer Ther.11(4),1036-1047(2012)
