Rucaparib phosphate
Cat. No.：YN290065
CAS No. ：459868-92-9
| 产品名称: | Rucaparib phosphate |
| CAS No.: | 459868-92-9 |
| Chemical Name: | 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one, phosphate |
| Synonyms: | AG-014699 phosphate; PF-01367338 phosphate |
| 分子量: | 421.36 |
| 分子式: | C₁₉H₂₁FN₃O₅P |
| SMILES: | O=P(O)(O)O.FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rucaparib phosphate (AG-014699 phosphate) 是一种具有口服活性的、有效的PARP抑制剂，结合 PARP1 的Ki为 1.4 nM，对其他八种 PARP 结构域也有亲和性。 |
| IC50和靶点: | [{name:"PARP-1:1.4 nM (Ki)'}, 'PARP-2', 'PARP-3'] |
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