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Nudifloramide

Cat. No.:YN310137

  • CAS No. :701-44-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Nudifloramide
      CAS No.: 701-44-0
      Chemical Name: 1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxamide
      Synonyms:2PY
      分子量:152.15
      分子式:C₇H₈N₂O₂
      SMILES:O=C(C(C=C1)=CN(C)C1=O)N
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Nudifloramide (2PY) 是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的最终产物之一。Nudifloramide 在体外可显著抑制PARP-1活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Giner, M.P., Christen, S., Bartova, S., et al.A method to monitor the NAD+ metabolome - from mechanistic to clinical applicationsInt. J. Mol. Sci.22(19),10598(2021)

      Lenglet, A., Liabeuf, S., Bodeau, S., et al.N-methyl-2-pyridone-5-carboxamide (2PY)-Major metabolite of nicotinamide: An update on an old uremic toxinToxins (Basel)8(11),E339(2016)

      Rutkowski, B., Rutkowski, P., Słomińska, E., et al.Distribution of purine nucleotides in uremic fluids and tissuesJ. Ren. Nutr.20(5 Suppl),S7-10(2010)

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