Lupeol
Cat. No.：YN482555
CAS No. ：545-47-1
| 产品名称: | Lupeol |
| CAS No.: | 545-47-1 |
| Chemical Name: | (3β)-lup-20(29)-en-3-ol |
| Synonyms: | 羽扇豆醇; Clerodol; Monogynol B; Fagarasterol |
| 分子量: | 426.72 |
| 分子式: | C₃₀H₅₀O |
| SMILES: | C[C@]1([C@@]2(CC[C@@]3([H])C4(C)C)C)[C@@](CC[C@]2([H])[C@]3(CC[C@@H]4O)C)([H])[C@]([C@@H]5C(C)=C)([H])[C@](C)(CC5)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lupeol (Clerodol; Monogynol B; Fagarasterol) 是一个活跃的五环三萜，具有抗氧化剂, 抗肿瘤和抗炎活性。Lupeol 是一种有效的雄激素受体 (androgen receptor) 抑制剂，可用于癌症研究，特别是雄激素依赖表型 (ADPC) 和去势抵抗表型 (CRPC) 的前列腺癌。 |
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Tarapore, R.S., Siddiqui, I.A., Saleem, M., et al.Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeolCarcinogenesis31(10),1844-1853(2010)
He, Y., Liu, F., Zhang, L., et al.Growth inhibition and apoptosis induced by lupeol, a dietary triterpene, in human hepatocellular carcinoma cellsBio. Pharm. Bull.34(4),517-522(2011)
Ardiansyah, Yamaguchi, E., Shirakawa, H., et al.Lupeol supplementation improves blood pressure and lipid metabolism parameters in stroke-prone spontaneously hypertensive ratsBiosci. Biotechnol. Biochem.76(1),183-185(2012)
Lucetti, D.L., Lucetti, E.C., Bandeira, M.A., et al.Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) PlumelJ. Inflamm. (Lond.)7(60),1-11(2010)
