YK11
Cat. No.：YN480330
CAS No. ：1370003-76-1
规格
价格(RMB)
库存
| 产品名称: | YK11 |
| CAS No.: | 1370003-76-1 |
| Chemical Name: | (20E)-17α,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid, methyl ester |
| Synonyms: | (17ALPHA,20E)-17,20-[(1-甲氧基乙亚基)二(氧基)]-3-氧代-19-去甲孕甾-4,20-二烯-21-羧酸甲酯 |
| 分子量: | 430.53 |
| 分子式: | C₂₅H₃₄O₆ |
| SMILES: | O=C1CCC2C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(OC(C)(OC)O/5)C5=C/C(OC)=O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YK11 是androgen受体的部分激动剂，具有成骨活性。 |
| IC50和靶点: | |
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Kanno, Y., Hikosaka, R., Zhang, S.-Y., et al.(17α,20E)-17,20-[(1-Methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptorBiol. Pharm. Bull.34(3),318-323(2011)
Kanno, Y., Ota, R., Someya, K., et al.Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expressionBiol. Pharm. Bull.36(9),1460-1465(2013)
Yatsu, T., Kusakabe, T., Kato, K., et al.Selective androgen receptor modulator, YK11, up-regulates osteoblastic proliferation and differentiation in MC3T3-E1 cellsBiol. Pharm. Bull.41(3),394-398(2018)
