PF-06263276
Cat. No.：YN340020
CAS No. ：1421502-62-6
| 产品名称: | PF-06263276 |
| CAS No.: | 1421502-62-6 |
| Chemical Name: | |
| Synonyms: | PF 06263276;PF06263276;PF 6263276 |
| 分子量: | 566.63 |
| 分子式: | C₃₁H₃₁FN₈O₂ |
| SMILES: | FC1=C(O)C=C(CC)C(C2=CC(NN=C3C4=NC5=C(CN(C(C6=NC=C(N7CCCCC7)N=C6)=O)CC5)N4)=C3C=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-06263276 (PF 6263276) 是一种有效、选择性的pan-JAK抑制剂，对 JAK1、JAK2、JAK3 和 TYK2 的抑制作用IC50值分别为 2.2 nM、23.1 nM、59.9 nM 和 29.7 nM。 |
| IC50和靶点: | [{name:"JAK1:2.2 nM (IC50)"},{name: "JAK2:23.1 nM (IC50)"},{name: "JAK3:59.9 nM (IC50)"},{name: "Tyk2:29.7 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
